Bioinformatics Scientist - Oncology (100%)
Jobbeschreibung
Schlieren, Zürich, Schweiz
Molecular Partners
27.04.2024
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General information Reference 2024-156 Information about Molecular
Partners AGFounded in 2004 by a group of PhD students as a spin-off
from the University of Zurich, Molecular Partners AG is a thriving and
steadily growing clinical stage biotech company located in
Zurich-Schlieren (Switzerland) with 200 highly qualified employees. In
order to advance modern medicine and significantly improve the
management of serious diseases, we have developed and successfully
established a powerful new class of potent, specific and versatile
small protein therapies, called DARPin therapeutics. The continuous
development of a broad portfolio of therapeutic product candidates in
oncology, virology and ophthalmology based on the company’s
proprietary DARPin platform allowed a successful listing of the
company on the SIX Swiss Exchange and Nasdaq (ticker: MOLN). Next to
our own pipeline of drug candidates we have entered into
collaborations with leading international pharmaceutical companies,
including AbbVie, Amgen and Novartis. The highly dedicated,
multi-disciplined team at MP is committed to developing breakthrough
medicines for serious diseases.Position descriptionPosition title
Bioinformatics Scientist - Oncology (100%) Job descriptionWe seek an
experienced computational biologist/data scientist that will play a
key scientific role in advancing the MP pipeline by leveraging
innovative computational analyses and large scale genomic datasets to
empower data-driven decisions in collaboration with research,
translational and clinical colleagues. This individual will design and
execute workflows for analysis, statistical modeling and the
generation of hypotheses from high-dimensional molecular profiling
data to identify and validate targets in tumor types with high unmet
medical need, identify indications and patient subsets for drug
candidates and biomarkers for selecting patients and assessing drug
action. This challenging and diverse position will include the
following tasks and responsibilities:Integrate diverse data sources
(e.g., patient mutation, proteome and transcriptome profiling,
functional genomic screens) to identify new cancer targets for defined
patient populations for the application of DARPin
therapeutics;Collaborate with laboratory and in vivo scientists to
design, analyze, and interpret experiments to validate targets,
understand compound mechanism of action, and identify biomarkers for
patient selection and target engagement;Design and execute a strategy
for the generation of omics data from clinical studies, including
vendor outreach;Support clinical development teams with data analysis
and interpretation during early clinical trials;Gather, curate and
process publicly available datasets;Develop and implement analysis
pipelines for omics data analysis and biomarker identification; Stay
at the forefront of the field by benchmarking and implementing new
omics analysis and AI methods.Requirements For this position, we are
looking for a highly motivated individual bringing along:Ph.D. in
computational, statistical, biology, physics, bioinformatics, or a
related field with emphasis on biological data analysis;3+ years of
experience in immune oncology genomics data analysis; Good
understanding of cancer biology and immunology;Experience with
standard methods for bioinformatic data analysis and reference
datasets (oncology) for bulk, single cell and spatial gene expression,
mutations, and related platforms;Proficiency in R or Python;Good
knowledge of statistics and basic knowledge of machine learning
algorithms;Experience with primary processing pipelines and with cloud
computing platforms would be an advantage;Experience with applications
of NGS to protein engineering would be an advantage;Strong written and
verbal communication skills in English;Collaborative and self-directed
personalityHighly collaborative and team-oriented mindset with
curiosity to learn new tasks and drive innovation.This position
summary is not intended to be all inclusive. An employee may perform
other related duties as negotiated to meet the ongoing needs of the
organization.Our offerPartnership and collaboration are at the core of
our company, our research activities and our product candidates.
Molecular Partners offers an international working environment and the
opportunity to collaborate with outstanding individuals from numerous
disciplines, who contribute to our shared goals of scientific
excellence, respectful teamwork and personal aspiration. We foster
true innovation and creative thinking to advance our therapeutic
product candidates and continue to be inspired by the difference we
can make for our patients. At Molecular Partners you will discover a
challenging job, inspiring colleagues and a true purpose. If you are
interested in working at Molecular Partners, we are looking forward to
hearing from you! Please submit your detailed curriculum vitae via our
career portal.We only accept online applications.Position locationJob
locationSwitzerland, Zürich, SchlierenPreferred head hunter
clausePlease note Molecular Partners AG operates a list of preferred
recruitment partners. For those partners who have no valid, signed
agreement in place with Molecular Partners AG, all unsolicited
resumes, CVs, anonymous profiles, or any other candidate details
submitted through our website or to personal e-mail accounts of
employees of Molecular Partners AG (including any of its subsidiaries,
affiliates or related companies) are not subject to payment of any
form of introduction, placement or referral fees.Molecular Partners
AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.