Senior PK Scientist - Pharmacokinetics (100%)

General information Reference 2023-150   Information about Molecular Partners AGFounded in 2004 by a group of PhD students as a spin-off from the University of Zurich, Molecular Partners AG is a thriving and steadily growing clinical stage biotech company located in Zurich-Schlieren (Switzerland) with 180 highly qualified employees. In order to advance modern medicine and significantly improve the management of serious diseases, we have developed and successfully established a powerful new class of potent, specific and versatile small protein therapies, called DARPin therapeutics. The continuous development of a broad portfolio of therapeutic product candidates in oncology and ophthalmology based on the company’s proprietary DARPin platform allowed a successful listing of the company on the SIX Swiss Exchange (ticker: MOLN) and NASDAQ. Next to our own pipeline of drug candidates we have entered into collaborations with leading international pharmaceutical companies, including AbbVie, Amgen and Novartis. The highly dedicated, multi-disciplined team at MP is committed to developing breakthrough medicines for serious diseases.Position descriptionPosition titleSenior PK Scientist - Pharmacokinetics (100%)Job descriptionAs an addition to our skilled preclinical team, we are looking for a highly experienced and motivated Preclinical pharmacokinetic lead. In this role, you will lead our preclinical PK platform and you will set up, manage et complete all preclinical PK packages with the team in each project for novel therapeutics in cancer immunotherapy and Radioligand Therapy (RLT). As part of a multi-disciplinary team, you will be expected to interact with project teams and several collaborators as part of project development.This challenging and diverse position will include the following tasks and responsibilities:Lead preclinical PK platform;Set up, manage, and complete preclinical PK packages for novel therapeutics in cancer immunotherapy and RLT;Interact with project leaders and different departments (LG, In vitro, Preclinical platforms, Translational and Clinical teams) to align, plan and execute the adequate preclinical PK package;Ensure highest quality of data;Independently execute designed experiment plans and interpret study observations;Effectively record and report experiments;Summarize and present data packages to the project team for discussion;Actively interact and work closely with team members to establish requirements and work-plans to support the development of project-specific assays;Keep up with state-of-the-art practices/technologies and ensure appropriate methods are utilized to obtain maximum effectiveness for preclinical sample analysis, including identification, evaluation and selection of relevant CROs.This position summary is not intended to be all inclusive. An employee may perform other related duties as negotiated to meet the ongoing needs of the organization.Requirements For this position, we are looking for an enthusiastic and highly skilled individual who features the following credentials:PhD degree in biological science;7+ years of experience on preclinical PK;Experience in PK/PD modeling is a plusExperience with the planning and conducting of preclinical drug development studies, including design and execution of a DMPK strategy7+ years of experience in a biopharmaceutical environment;Background in tumor biology or cancer immunology is mandatory,Background in Radioligand Therapy is a plus;Open communication and team-orientated;Proactive and independent working style;Experience working in an agile environment;Reliable and well-organized;Familiar with MS-Office programs;Flexible with ability to quickly become acquainted with new tasks;Solid knowledge of English.Our offerPartnership and collaboration are at the core of our company, our research activities, and our product candidates. Molecular Partners offers an international working environment and the opportunity to collaborate with outstanding individuals from numerous disciplines, who contribute to our shared goals of scientific excellence, respectful teamwork, and personal aspiration.We foster true innovation and creative thinking to advance our therapeutic product candidates and continue to be inspired by the difference we can make for our patients.At Molecular Partners you will discover a challenging job, inspiring colleagues, and a true purpose. If you are interested in working at Molecular Partners, we are looking forward to hearing from you! Please submit your detailed curriculum vitae via our career portal.We only accept online applications.Position locationJob locationSwitzerland, Zürich, SchlierenPreferred head hunter clausePlease note Molecular Partners AG operates a list of preferred recruitment partners. For those partners who have no valid, signed agreement in place with Molecular Partners AG, all unsolicited resumes, CVs, anonymous profiles, or any other candidate details submitted through our website or to personal e-mail accounts of employees of Molecular Partners AG (including any of its subsidiaries, affiliates, or related companies) are not subject to payment of any form of introduction, placement or referral fees.Molecular Partners AG, Wagistrasse 14, CH-8952 Zurich-Schlieren, Switzerland.