Snr Principal Scientist Translational Research/Immunology (80-100%*)
Jobbeschreibung
Basel, Basel-Stadt, Schweiz
Novartis
03.05.2024
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About the roleLocation: Basel, SwitzerlandFull time, onsite,
#LI-OnsiteThe Immunology Department (IMM-DA) at Novartis has a strong
track record in discovery and development of novel therapies for the
treatment of autoimmune and inflammatory diseases. We are looking for
an experienced Immunologist for our Translational Research (TR) group.
The TR group is an integrated group of scientists with strong
expertise in in vivo Pharmacology, Molecular Pathology,
disease-relevant in vitro models, and Data Science. The TR group
conducts preclinical experiments and uses patient data and human
biosamples to support the compound portfolio of IMM-DA end-to-end. The
candidate will lead a lab and generate key translational insights on
the next wave of therapies for patients with autoimmune and
inflammatory diseases. The ideal candidate will have a strong
background in preclinical in vivo pharmacology and will closely
collaborate with the other disciplines in the TR group to successfully
advance novel therapies into the clinics. Industry experience in drug
discovery of biologic and low molecular weight therapies is of
advantage. Responsibilities: • Generate preclinical in vivo and
translational data in support of key portfolio projects.• Address key
translational research questions for novel drugs related to mechanisms
of action, asset differentiation, in vivo PK/PD relationship and
exploratory biomarkers from animal studies and/or patient samples.•
Represent TR on program discovery and development teams. Lead a target
discovery effort or drug discovery project from a translational
perspective. Contribute to the overall department’s strategic
direction with special focus on increasing the impact of translational
research approaches in drug discovery and development.• Lead internal
and external collaborations to increase team capabilities or address a
strategic need.• Take initiative to identify, pilot and internalize
emerging technical approaches that may drive increased value for
portfolio execution.• Prepare and/or direct the preparation and review
of Preclinical Pharmacology sections of IBs, INDs, abstracts, and
manuscripts.Commitment to Diversity & Inclusion:We are committed to
building an outstanding, inclusive work environment and diverse teams
representative of the patients and communities we serve.Role
RequirementsWhat you will bring to the role:• Ph.D. or MD/PhD with
PostDoc in Immunology, Pharmacology, or related discipline plus >5
years of professional experience in academia or industry.• Expert
understanding of in vivo disease models and experience in performing
mechanistic studies in rodent models of autoimmune and inflammatory
diseases is required.• Immunology/autoimmune disease knowledge,
including target and mechanism knowledge (e.g. SLE, arthritis, atopic
dermatitis) and awareness of clinical standard of care.• Understanding
of fundamentals and practice of the drug discovery process in pharma
industry is of advantage.• Excellent written and oral communication
skills.• Self-motivated and collaborative, with excellent time
management and interpersonal skills.Why Novartis:Our purpose is to
reimagine medicine to improve and extend people’s lives and our vision
is to become the most valued and trusted medicines company in the
world. How can we achieve this? With ourpeople. It is our associates
that drive us each day to reach our ambitions. Be a part of this
mission and join us! Learn more he re: and cultureYou’ll receive: You
can find everything you need to know about our benefits and rewards in
the Novartis Life Handbook. rewardscommunities we serve.Join our
Novartis Network: If this role is not suitable to your experience or
career goals but you wish to stay connected to hear more about
Novartis and our career opportunities, join the Novartis Network here:
and accommodationNovartis is committed to working with and providing
reasonable accommodation to all individuals. If, because of a medical
condition or disability, you need a reasonable accommodation for any
part of the recruitment process, or in order to receive more detailed
information about the essential functions of a position, please send
an e-mail to and let us know the nature of your request and your
contact information. Please include the job requisition number in your
message.DivisionBiomedical Research Business UnitIMMUNOLOGY - NIBR
Work LocationBasel Company/Legal EntityNovartis Pharma AGFunctional
AreaResearch & Development Job TypeFull TimeEmployment TypeRegular
Shift WorkNoEarly TalentNoCountry: Switzerland
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Snr Principal Scientist Translational Research/Immunology (80-100%*)
Novartis
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