112 jobs in Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
Roche Diagnostics International AG in Rotkreuz is one of the world's leading providers of diagnostic system solutions for hospitals, laboratories, and physician offices. With over 2,200 employees, Rotkreuz is one of Roche Diagnostics' main sites, making it the largest manufacturer of fully automated in vitro diagnostic systems in Switzerland with more than 2,700 passionate colleagues from over 65 nationalities. At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare, working together as one of the world's leading research-focused healthcare groups where success is built on innovation, curiosity, and diversity. We believe in the power of diversity and inclusion, striving to identify and create opportunities that enable all people to bring their unique selves to Roche, while offering extensive development and training opportunities, flexible working options, 18 weeks of maternity leave, 10 weeks of gender independent partnership leave, and multiple on-site services such as child-care facilities, medical services, restaurants, cafeterias, and various employee events.
In this highly specialized permanent, full-time role as Senior Specialist - Tech Transfer & Manufacturing Science (SBX Sequencing) within the DODINL Production Laboratory & QC line organisation led by Eric Wanko, you will be the key technical anchor for the critical technology transfer of advanced genetic sequencing workflows. As part of Roche's global Dual-Site Strategy, we are expanding our manufacturing footprint to establish parallel production capabilities, where this transfer to Rotkreuz, Switzerland, is designed to complement and work in tandem with our existing operations in Santa Clara, USA, ensuring long-term global supply security and scaling our production capacity across both key sites. In this position, you will act as the ultimate Subject Matter Expert (SME) for the technical execution, optimization, and scaling of our proprietary sequencing consumable portfolios in Europe, leveraging your deep, pre-existing technical knowledge of our US-developed manufacturing lines to ensure seamless cross-site standardization as a central part of a genius team and shaping role.
**The Opportunity**
+ Technology Transfer & Site Alignment: Drive the technical transfer of RUO (Research Use Only) and regulated genetic sequencing workflows (specifically SBX sequencing chemistry) from Roche Santa Clara (US) to the Rotkreuz site, ensuring absolute process alignment between both operating sites.
+ Subject Matter Expert (SME): Serve as the primary technical authority for drafting, reviewing, and auditing site-specific operating procedures (SOPs), batch record templates, and work instructions for critical consumable components.
+ Process Optimization & Scaling: Manage and execute complex experiments throughout the product lifecycle, from initial feasibility and stability testing through to official launch and routine manufacturing transfer.
+ Advanced Quality Control: Oversee high-priority investigations into complex process failures or manufacturing deviations, applying advanced statistical techniques and data analysis to implement robust Corrective and Preventive Actions (CAPA).
+ Cross-Functional Training: Translate development workflows into standardized work procedures, providing deep technical guidance and training local operators on complex reagent handling, raw material formulation, automated dispensing, and data analyzation.
+ End-to-End Quality Inspection: Act as the final technical gatekeeper for complex diagnostic portfolios, ensuring strict adherence to compliance standards, including final inspections of specialized testing frameworks.
**Who You Are**
+ Regulated Industry Expert: Seasoned scientist with comprehensive experience driving operations within strict cGMP, ISO 13485, and QSR-compliant biotech and molecular diagnostics environments.
+ End-to-End Quality Mindset: Proven track record in executing rigorous in-process quality control (QC), raw material stability testing, and final product inspections to ensure total regulatory compliance.
+ Analytical Problem Solver: Highly skilled in managing nonconformances and deviations, utilizing data-driven root-cause analysis to implement effective corrective and preventive actions (CAPA).
+ Process & Efficiency Optimizer: Demonstrated success in process improvement and technology transfer projects, with a history of leveraging ERP systems (SAP) to measurably reduce production timelines and costs.
+ Documentation & Compliance Anchor: Expert in the end-to-end lifecycle of critical manufacturing documentation, including drafting, cross-functional review, and approval of batch records and SOPs.
+ Adaptable Technical Skills: Proficient in both high-precision manual laboratory techniques and the operation, maintenance, and troubleshooting of high-throughput automated instrumentation.
+ Cross-Functional Collaborator: Adept at bridging gaps between R&D, Quality Assurance, and Engineering teams to ensure seamless internal product transfers and hit aggressive deadlines.
+ Workflow Coordination & Mentorship: Experienced in synchronizing cross-functional workflows, overseeing production lines, and designing training schedules to upskill team members on GMP compliance.
**Ready for the next step? We look forward to hearing from you. Apply now to discover this exciting opportunity!**
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

**The Position**
Join the small-molecule team within AI for Drug Discovery (AI4DD), formerly Prescient Design, at Roche and Genentech's Computational Sciences Center of Excellence as a Machine Learning Scientist / Senior Machine Learning Scientist building agents for applied small-molecule drug design. You will develop autonomous, LLM-driven agentic workflows that orchestrate ML models, physics-based methods, and cheminformatics tools to accelerate discovery, working with world-class chemists and structural biologists.
**The Opportunity:**
+ **Design, build, and apply agentic workflows and ML models** for key challenges in small-molecule drug design.
+ **Fine-tune foundation models for drug discovery** relevant topics using internal and external datasets and tools.
+ **Optimize agent-derived hypotheses** in close collaboration with world-class computational and medicinal chemists and structural biologists.
+ **Drive scientific impact** through publications, open-source releases, and conference talks.
+ **Collaborate widely** with computational and experimental researchers at Roche and with academic partners.
**Who you are:**
+ You are experienced developing LLM-driven agents for scientific workflows and you understand how to orchestrate tools and models reliably.
+ You bring strong machine-learning foundations in linear algebra, probability and optimization, with hands-on experience with GNNs, sequence/language models and reinforcement learning.
+ You are fluent in Python and modern agentic coding environments such as LangChain, ML frameworks such as PyTorch or JAX, as well as cheminformatics toolkits like RDKit or OpenEye.
+ You hold a PhD or equivalent research depth in machine learning, computer science, chemical engineering or a related quantitative field such as physics or statistics.
+ You have a record of scientific excellence evidenced by journal and conference publications or a public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).
**Preferred:**
+ Hands-on experience orchestrating multi-tool or multi-agent scientific pipelines.
+ Hand-on experience working along the small molecule drug discovery value chain and an excitement to engage with chemists
+ Familiarity with structural biology datasets
If you want to put autonomous AI to work discovering the medicines patients need next, apply now and help build the future of drug design at Roche.
**_The expected salary range for this position based on the primary location of California for the Machine Learning Engineer is $147,600, - $274,000, and the Senior Machine Learning Engineer for California is $167,400 - $310,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below._**
Benefits ( pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is San Francisco. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants ( .

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
In a global, cross-functional environment, the PCR Software Development chapter develops, delivers, and maintains integrated, unified, and reliable software solutions for Molecular Diagnostics Systems. By leveraging our advanced capabilities and strong internal and external partnerships, we drive accuracy and agility in innovating the Molecular Lab experience for our customers and patients.
**The Opportunity**
As a Senior Vendor Manager and Project Leader, you will drive the collaboration, compliance, and performance of third-party engagements within Roche Diagnostics Solutions R&D. Acting as the primary interface between the vendor's delivery manager and Roche, you ensure external partners deliver according to contractual obligations and industry best practices while aligning internal stakeholders to guarantee overall project success.
This role is based in Rotkreuz, Switzerland, with a hybrid working model expecting approximately 50% on-site presence. Your contributions will directly support the Roche Diagnostics 10-year ambition.
In this position, you will be responsible for the following areas:
+ You build strong, collaborative vendor partnerships based on transparency and trust, driving daily alignment, stakeholder connections, and domain onboarding.
+ You manage operational oversight by conducting regular review meetings and Quarterly Business Reviews (QBRs) to ensure long-term contractual compliance.
+ You partner with vendors and Roche Procurement to draft work orders and Service Level Agreements (SLAs) tied to "at-risk" amounts for maximum accountability.
+ You verify invoicing accuracy against milestones and "at-risk" delivery outcomes to prevent budget overruns.
+ You establish and monitor robust metrics to track feature progress, value realization, and the alignment of development efforts with contractual milestones.
+ You guard against scope creep, strictly aligning SOW requirements with the agile backlog while balancing fixed-price constraints and agile flexibility.
+ You lead moderate-sized squads or ARTs, taking full accountability for delivering engagements within schedule, scope, budget, and quality constraints.
+ You enforce a Quality-First framework (e.g., defect density, V&V rates, technical debt) to ensure vendors prioritize product integrity over pure velocity.
**Who You Are**
You are a dynamic professional who thrives in complex, multi-faceted environments and possesses a "win-win" partnership mindset.
Your skills and experience include:
+ You hold a Bachelor's degree in Engineering, preferably in the field of Computer Science.
+ You hold a project management certification such as PMP, IPMA Level B, or equivalent (SAFe certifications like Leading SAFe are a strong plus).
+ You possess in-depth conceptual and practical knowledge of software engineering, preferably within IVD, regulated environments, agile setups (SAFe), and project management.
+ You bring a proven track record in near- or offshore software projects and vendor management, backed by excellent intercultural communication skills.
+ You demonstrate a strong experience in defining and measuring quality-driven KPIs, understanding that "done" means compliant, maintainable, and high-quality.
+ You prevent scope creep through rigorous change control and negotiation with internal and external stakeholders to successfully maintain project boundaries.
+ You foster an inclusive and psychologically safe environment, motivated to make a real impact on fellow team members, our company, and our patients.
+ You are willing and able to travel internationally approximately once per quarter to visit nearshore/offshore partners and strengthen collaboration.
Are you ready to make an impact? Apply now and join us in shaping the future of laboratory and near-patient diagnostics! Please submit your CV to complete your application.
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
We are currently seeking a Clinical Scientist to join our global team based in Basel in the Early Development department in the Neuroscience and Rare Disease DTA. This role will primarily support our latest development priorities.
We are a dedicated, collaborative team focused on meaningful lifecycle innovations that directly impact the neuroscience community. This position offers the opportunity to contribute to established science while addressing unmet needs in the Parkinson's, Alzheimer's, multiple sclerosis, and rare disease community.
The Opportunity
+ Provide support in developing and/or preparing clinical science information for inclusion into the Clinical Development Plan.
+ Guided by the Lead/senior Clinical Scientist, contribute to protocol/ICF (writing or amendment), construct appropriate CRFs and coordinate cross-functionally.
+ Guided by the Lead/senior Clinical Scientist, contribute to internal/external clinical presentations and communications (e.g. investigator meetings, study site interactions, patient information, study newsletters). Present at appropriate internal meetings, e.g. Study Leadership Team. Contributes to abstracts, posters, content for scientific meetings.
+ Work with Lead/senior Clinical Scientists/Medical Directors/Clinical Directors and cross-functional groups to execute the Medical Data Review Plan, data interpretation and contribute to study reporting.
+ Work as medical monitor of phase 1 and phase 2 clinical trials in Parkinson's and Alzheimer's disease
+ Work on advanced imaging technique to measure neurodegeneration (e.g. neuromelanin-MRI) in Parkinson's and Alzheimer's disease
+ With guidance, contribute to Clinical Trial Application (CTA)/Ethics Committee (EC) written interactions, briefing packs, written responses to Health Authority (HA) questions, clinical science data/preparations for HA interactions and clinical data input to regulatory submissions.
Who you are
+ Degree in Medicine required (e.g. MD, MBBS). An advanced clinical/Science Degree is highly preferred (e.g. PhD, PharmD, MSN, MPH, etc.).
+ 1 to 3 years of clinical development experience. While prior experience is a plus, we are primarily looking for someone with high potential, strong motivation, and a willingness to learn
+ Familiarity with governing laws, regulations, guidelines on global clinical trial execution is required and some knowledge of medical aspects of GCP (Good Clinical Practice), ICH (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use), FDA, EMA and other relevant guidelines and regulation.
+ Good understanding of the multidisciplinary functions involved in drug development. Some therapeutic area relevant clinical trial experience or clear potential to assimilate with some support.
+ Strong collaborative skills with the ability to work effectively within a geographically distributed global team.
Are you ready to make a difference for our patients? We are looking forward to your application - join us now and become part of our journey!
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
**The Opportunity**
At Roche, we advance science so that we all have more time with the people we love. In Pharma Development Quality (PDQ), we strive for confidence in the integrity of our data and processes, agility, and unrivalled transparency with health authorities, patients, and society. As a Senior Quality Lead within our Quality Assurance Process and Affiliate team, you will bring diverse thinking and technical expertise across various quality disciplines to support the Roche/Genentech organisation.
In this pivotal role, you will design and deliver risk-based Quality Assurance strategies, audits, and conclusions for post-approval products, affiliates, and processes. You will act as a trusted partner to senior business stakeholders, guiding cross-functional collaboration to ensure global quality standards are met while navigating complex regulatory landscapes.
+ **Design and Implement QA Strategies:** Partner with business stakeholders to independently define the QA approach, assessing risks and adapting strategies using the Critical to Quality (CtQ) framework across GCP, GVP, and Medical Device areas.
+ **Define and Lead Audits:** Determine required audits, leverage data analytics to develop methodologies, and independently manage the end-to-end audit process from preparation to reporting.
+ **Manage Quality Issues:** Independently manage quality issues, tracking systematic findings for process improvement and escalating significant risks to PDQ management.
+ **Quality Conclusion and Stakeholder Communication:** Independently evaluate quality positions to drive compliance action plans. Lead high-level risk presentations and strategic discussions with business stakeholders, Pharma representatives, Legal, and Regulatory Affairs.
+ **Lead and support Health Authority Inspections:** Lead preparation, staff training, and the management of major regulatory inspections (e.g., FDA, EMA), confidently presenting quality strategies and conclusions.
+ **Drive PDQ Leadership & Mentorship:** Contribute to the long-term strategic direction of PDQ, lead compliance projects, and act as a dedicated mentor to develop Quality Leads within the team.
**Who You Are**
You are a proactive, strategic thinker who thrives in a collaborative, matrixed environment and is passionate about driving Quality outcomes. You possess strong digital and data literacy, allowing you to turn data into insights, and you are comfortable asking challenging questions to support PDQ outcomes.
To be successful in this role, you bring:
+ **Extensive Quality Expertise:** A strong background in the drug development process and clinical trials, with robust cross-functional experience in GCP, GVP/PV, or Medical Devices/SaMD.
+ **Inspection Leadership:** A proven track record of leading major Health Authority inspections (such as FDA or EMA), including inspection readiness and post-inspection management.
+ **Analytical & Critical Thinking:** Advanced problem-solving skills with a proactive, risk-based mindset and the ability to utilise data and data visualisation tools to drive decisions.
+ **Influencing & Communication Skills:** Exceptional relationship management skills with a proven ability to negotiate effective solutions and influence senior stakeholders.
+ **Inclusive Leadership:** Experience managing projects in global, multicultural teams, with a passion for coaching and mentoring others.
+ **Academic Qualifications:** A Bachelor's degree or equivalent in a scientific or quality-related field (an advanced degree is preferred).
Location
+ This position is based in Welwyn, Basel, SSF or Mississauga.
+ Relocation Assistance is not available.
+ \#MQRS
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
This role is based in the Innovation Accelerator (IA) team, the innovation engine and connective tissue for Design, Data and Data Science innovation strategy within Product Development Data Sciences (PDD). We translate our long-term PDD vision into actionable strategy, shaping and prioritizing innovative cross-functional use cases that span PDD, PD, and Pharma. As both integrators and incubators, we explore, prototype, and help productize solutions to deliver impact in close partnership with internal Roche teams and external collaborators. With a mindset rooted in openness, value creation, and adaptability, we navigate the innovation ecosystem to drive transformative impact and future readiness across the organization.
**The Opportunity:**
+ You lead the design, development, and deployment of AI/ML agents that drive workflow efficiencies and operational insight
+ You identify high-impact opportunities for automation across the R&D data ecosystem and translate them into technical solutions
+ You design intelligent process monitoring and optimization pipelines leveraging structured and unstructured data
+ You prototype and productize AI agents that support internal users across PDD, including metadata enrichment, task routing, or data retrieval
+ You apply advanced techniques in NLP, system optimization, or process analytics in real-world business contexts
+ You collaborate with engineering, domain experts, and business stakeholders to ensure feasibility, usability, and value delivery
+ You contribute to cross-functional initiatives by representing the AI operations strategy and fostering scalable solution design
+ You provide technical leadership, share best practices, and guide junior colleagues in navigating operational AI use cases
**Who you are:**
+ You have a Bachelor's or advanced degree in Computer Science, Machine Learning, Engineering, Biomedical Informatics, or a related field
+ You have a minimum of 8 years of experience designing and delivering AI/ML solutions with measurable operational impact; or an advanced degree with 6 years of equivalent work experience
+ You have deep expertise in Python software development or similar languages and AI libraries (e.g., PyTorch, Tensorflow, scikit-learn, Transformers, RAG toolkits Langchain/Langgraph, Autogen)
+ You have a track record of applying AI or automation to optimize internal workflows or business processes
+ You are familiar with operational data, ML pipelines, and AI productization frameworks
+ You have a deep understanding of model reproducibility, interpretability, and validation best practices
+ You have capacity for independent thinking and ability to make decisions based upon sound principles
Relocation benefits are not available for this posting
\#PPDT
\#PDDBasel
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
Als Automation Engineer bist du im Bereich "Business Solutions" und dort im Circle "Pharma Engineering Solutions" des Standortes Basel / Kaiseraugst tätig. Der Bereich "Business Solutions" der Roche Pharma ist am Standort Basel/ Kaiseraugst verantwortlich für innovatives, kostengünstiges und GMP-gerechtes Planen und Umsetzen von Investitionsprojekten. Darüber hinaus realisiert der Bereich das Gebäude- und Betriebsingenieurwesen, das technische Qualitätsmanagement und ist verantwortlich für eine zuverlässige Störungsbehebung und Instandhaltung, inklusive dem Betreiben der erforderlichen Infrastruktur. Wir unterstützen unser Management und unsere Kunden bei biotechnologischen, chemischen und galenischen Produktions-/ Verpackungsanlagen, Laborbauten und Administrationsbauten.
**Die Möglichkeit**
Als Automation Engineer betreust du bestehende und neue Automationssysteme, welche in die Roche Infrastruktur integriert sind/werden. Die zu betreuenden Prozessanlagen verfügen über einen sehr hohen Automatisierungsgrad und sind stark untereinander bzw. mit übergeordneten IT Systemen vernetzt.
Ihr Hauptaufgabengebiet umfasst:
+ Leitung und Abwicklung von Automationsprojekten in allen Projektphasen wie Initiierung, Design und Realisierung (selbständig und mit Unterstützung von internen und externenSpezialisten)
+ Zusammenarbeit mit Schnittstellen bei Projekten und Change
+ Implementierung von Automationssystemen in die Roche Infrastruktur
+ Anbindungen der Automationssysteme an den Data Historian
+ Strategie und Aufrechterhaltung des Lifecycles von PC basierten Automationssystemen
+ Unterstützung unserer internen Kunden bei technischen Fragen sowie bei Behördeninspektionen Betriebsengineering mit dem Ziel, die Aufrechterhaltung der Produktion jederzeit zu gewährleisten
+ kontinuierliche Optimierung der Prozessanlagen und Evaluieren, Prüfen und Empfehlen neuer Technologien
+ proaktives Unterstützen der Kunden bei der Definition und Initiierung von Investitionsvorhaben
**Wer du bist**
Du besitzt eine fundierte Grundausbildung mit abgeschlossenem Studium (FH/TU) in Automation oder Informatik oder die entsprechenden Kenntnisse sowie mind. 5 Jahre Berufserfahrung in der Automation oder Informatik.
Du bist vertraut mit der Abwicklung von Investitionsprojekten, insbesondere mit der Beschaffung von Package Units.
+ Du hast die technische Expertise von Netzwerktechnik und Automationssoftware: Siemens PCS7, S7, TIA, WinCC (***)
+ Du bringst mehrjährige Erfahrung als Projektleiter mit
+ Fundierte Erfahrung im GMP- und GAMP- Umfeld
+ Teamfähigkeit und sehr gute Kommunikations- und Koordinationsfähigkeiten innerhalb der Organisation sowie ein angemessener Umgang mit Stakeholdern auf allen Ebenen
+ Bereitschaft im agilen, selbstorganisierten Arbeitsumfeld zu arbeiten
+ Du verfügst über gute Deutsch- und Englischkenntnisse in Wort und Schrift
Setze dein Know-how ein und gestalte den Bereich 'Pharma Engineering Solutions' am Standort Basel / Kaiseraugst mit. Bewirb dich jetzt !
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
Join the small-molecule team within AI for Drug Discovery (AI4DD), formerly Prescient Design, at Roche and Genentech's Computational Sciences Center of Excellence as a Machine Learning Scientist / Senior Machine Learning Scientist in Small Molecule Drug Design. You will develop and apply ML methods and models to accelerate small-molecule drug design with a focus on structure-driven approaches, working hand in hand with world-class computational and medicinal chemists and structural biologists.
**The Opportunity:**
+ **Design, build, and apply cutting-edge ML models** for small-molecule drug design, focused on protein-ligand interactions, binding affinity and key molecular properties.
+ **Train and fine-tune foundation models** for structure prediction, using internally developed and open-source models on internal datasets.
+ **Validate and refine ML-generated hypotheses** alongside world-class computational and medicinal chemists and structural biologists.
+ **Drive scientific impact** through publications, open-source releases, and conference talks.
+ **Collaborate widely** with computational and experimental researchers at Roche and with academic partners.
**Who you are:**
+ You bring deep machine-learning expertise with a strong foundation in linear algebra, probability and optimization, and hands-on experience designing & implementing machine learning approaches such as graph neural networks, sequence models, and reinforcement learning.
+ You have structure-driven modelling experience with co-folding methods, binding-affinity prediction, and structural-biology datasets.
+ You are fluent in Python and cheminformatics with toolkits such as RDKit and OpenEye, and modern ML frameworks like PyTorchor JAX.
+ You hold a PhD or equivalent research depth in machine learning, computational chemistry, chemical engineering or a related quantitative field such as physics or statistics.
+ You have a record of scientific excellence evidenced by journal and conference publications or a public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).
**Preferred:**
+ Hands-on experience building structure-prediction foundation models.
+ Experience collaborating directly with medicinal chemists and structural biologists.
If using AI to design the medicines patients need next inspires you, apply now and help accelerate small-molecule discovery at Roche.
\#ComputationCoE
\#tech4lifeComputationalScience
\#tech4lifeAI
Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
**Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
**The Position**
Join the small-molecule team within AI for Drug Discovery (AI4DD), formerly Prescient Design, at Roche and Genentech's Computational Sciences Center of Excellence as a Machine Learning Scientist / Senior Machine Learning Scientist in Quantum Chemistry. You will combine machine learning methods and quantum chemistry to build fast, accurate models that power small-molecule drug discovery. You will work with world-class computational and experimental scientists and leverage proprietary datasets and state-of-the-art compute.
**The Opportunity:**
+ **Create cutting-edge solutions** that combine quantum chemistry and machine learning algorithm development to model small-molecule energetics and protein-ligand interactions, from conformation and reactivity to binding affinity and free energy.
+ **Build synthetic datasets using quantum mechanics** and related methods to shape novel research directions in ML.
+ **Develop deployable pipelines** that are robust, scalable and reproducible, and feed directly into molecular-design tools used across Roche.
+ **Drive scientific impact** through publications, open-source releases, and talks at internal and external conferences.
+ **Collaborate widely** with world-class computational and experimental researchers at Roche and with academic partners.
**Who you are:**
+ You bring deep machine-learning expertise with a strong theoretical foundation in linear algebra, probability and optimization, and you build models from first principles.
+ You have hands-on quantum chemistry experience and fluency in toolkits such as Psi4, PySCF and ORCA, as well as semi-empirical methods like xTB.
+ You are fluent in Python and modern ML frameworks such as PyTorch or JAX.
+ You hold a PhD or equivalent research depth in machine learning, computational chemistry, chemical engineering or a related quantitative field such as physics or statistics.
+ You have a record of scientific excellence evidenced by journal and conference publications or a public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).
**Preferred:**
+ Experience in scientific software development, scaling ML training, and applying models to drug discovery.
+ Experience generating large-scale synthetic datasets.
If building physics-grounded machine learning models that bring better medicines to patients faster is your calling, apply now and help shape the future of small-molecule drug discovery.
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Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Welwyn. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.
**Who we are**
A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let's build a healthier future, together.
The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants' requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.